Importance of Particle Size Distribution in Pharmaceutical Industry
Innovative drug development in the 21st century is a long, laborious process.
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Size & Volume Reduction
Size reduction equipment innovations for dry material handling operations
There are numerous industries that depend on size reduction or comminution of bulk solids to improve performance or to meet specifications. There are many types of size-reduction equipment, which are often developed empirically to handle specific bulk materials and then are applied in other settings. Knowing the properties of the material to be processed is essential. Despite the availability of other particle production processes, size reduction remains today one of the workhorses for production of bulk solids with tailored particle properties.
Particle forming / size enlargement equipment innovations for dry material handling operations
Agglomeration or size enlargement processes transform small bulk solids or past materials to materials of larger sizes, with either random or controlled shapes - granules, briquettes, tablets, pellets, bricks, extrudates or compacts. Size enlargement is a process that has been used for centuries and in many ways, it still remains an art rather than an exact science. Perhaps this is due to the unpredictable behavior of bulk solids. Also in this process, determination of the required product properties is of utmost importance. This Technology Zone offers an insight into the latest innovations in size reduction and size enlargement techniques and equipment to assist you when handling dry bulk materials.
Articles about Size & Volume Reduction
Pulverize, Grind, Crush or Mix Wet, Sticky or Dry Materials
The Stedman H-Series multi cage mill is best at pulverizing, grinding, crushing and mixing abrasive and non-abrasive materials – wet, sticky or dry.
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Recent Size and Volume Reduction e-newsletters
Read our last “Size and Volume Reduction” e-newsletter campaigns here:
Particle Engineering: Industry’s Golden Goose
What is particle engineering? – Particle engineering is the science of altering particles into the desired shape, size distribution or composition as well as other aspects of the particle’s morphology and surface characteristics.
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Small-Scale Ball Mill Circuits, Jet Mills and Air Classifier Systems for Laboratory Applications
Comex has developed different small-scale comminution system employing ball mills, jet mills and air classifiers, for laboratory use. The equipment is very compact, requires small amount of input material and the operating system provides fully automatic test procedures with registration of all operating parameters in the control unit.
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Process Equipment Manufacturer Unveils Line of Hygienic Lump Breakers
The Nibbler line of lump breakers from process equipment manufacturer Gericke USA, Somerset, NJ, is offered in optional hygienic designs for installation in sanitary processing facilities.
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New, Efficient Process for the Rounding of Graphite
Due to its use as a material for anodes in lithium-ion-batteries, graphite is of great importance in the context of electromobility. In order to obtain the high purity required for battery applications, the finely-distributed, so-called flake graphite which occurs naturally in stone, must be processed in various steps.
Read moreExperts for Size & Volume Reduction
Todd Allison (Progressive Products, Inc)Todd Allison is President of Progressive Products, Inc, having moved from sales to take the leadership role and successfully driven the company’s growth over the last 10 years. Todd also leads the Apex Stages brand, part of Progressive Products, and was an adjunct professor in the Technology and Workforce Development Department at Pittsburg State University, where he taught Innovation Engineering. Todd has spent most of his life in the pneumatic conveying industry and has over 15 years of experience in industrial sales and product design. He is a graduate of SCAD design school and attended the Kelce School of Business at Pittsburg State University. He serves on several advisory boards including the CEDBR Kansas Economic Outlook Team and the Mid America District Export Council. Todd’s passion outside of work lies in photography, and he has been a freelance photographer since the early 1990s. He specializes in editorial, portrait, product, and fine art photography.
Chris Nawalaniec (Stedman Machine Company)Chris Nawalaniec is Vice President of Sales and Marketing at Stedman Machine Company, the Aurora, Ind.-based manufacturer of size reduction equipment and systems, founded in 1834. Nawalaniec graduated from the University of Cincinnati (BSME, MBA) and has more than 30 years professional experience in size reduction and particle size separation. Nawalaniec oversees new machinery and system sales, as well as the full-service test plant that has been operating at Stedman for more than 90 years.
Joe Muscolino (Sturtevant Inc.)Joe Muscolino is Senior Product Manager of Air Classifiers with Sturtevant Inc., the leading international manufacturer of powder processing equipment including, crushers, fine grinders and air classifiers. With over 25 years of industrial experience, his expertise in applying air classifiers and mills is recognized throughout the world. Joe specializes in helping customers identify the most cost effective means for completing their projects.
Peter Raeven Ing. (Dinnissen Process Technology)28 years experience in development and realisation projects as a project manager for feed, aqua feed and petfood. Working at Dinnissen for 18 years as account manager in feed, aqua feed and petfood division. Specialist in developing major projects with added value focussing on pneumatic conveying, mixing, drying, grinding and coating with liquid and powder systems.
Fast and Reproducible Pulverization of Large Sample Volumes
No grinder can beat the speed of a Vibratory Disc Mill when it comes to preparing samples, e. g. for XRF analyses.
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General Kinematics’ VIBRA-BUSTER™ Vibratory Lump Breaker
Moisture Caking, Material Bond, Chemical Reaction, and Static Electricity can cause agglomerations in your material leaving you or your customers with a poor material presentation.
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New Hamex® Fully Automatic Hammer Mill Reduces Product Cost Price Thanks to Clever Re-design
Product cost price even lower due favourable hammer mill price, fewer operations when changing screens and more efficient milling.
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How to Effectively Scale-Up from Lab to Pilot to Production
In many pharmaceutical processes, what works in the lab doesn’t always scale-up seamlessly into production; this is true in conical milling. Larger batches, different process conditions, and varying material characteristics can all create unforeseen problems that ultimately impact performance.
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